Col4a1 CLIA Kit for Mouse(Mus musculus) | EIAab.comCol4a1 CLIA Kit for Mouse(Mus musculus)

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Col4a1 (Gene name),

Collagen alpha-1(IV) chain (Protein name ), CO4A1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Col4a1;

Protein name:

Collagen alpha-1(IV) chain;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network.

Function:

Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.

Subcellular Location:

Secreted extracellular space extracellular matrix basement membrane

Protein Attributes:

Sequence length:

1669

Sequence:

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1650:

1669:

KAGELRTHVS | RCQVCMRRT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P02463

UniGene:

Mm.738

Pfam:

PF01413

KEGG:

mmu:12826

String:

P02463

Uniprot:

P02463

FOR

ELISA Kit for Mouse Collagen alpha-1(IV) chain

Cat.:

E0180h

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Packing:

96T

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ELISA Kit for Mouse Collagen alpha-1(IV) chain

Cat.:

E0180m

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Packing:

96T

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ELISA Kit for Mouse Collagen alpha-1(IV) chain

Cat.:

E0180r

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96T

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ELISA Kit for Mouse Collagen alpha-1(IV) chain

Cat.:

E0180b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Collagen alpha-1(IV) chain

Cat.:

U0180m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Collagen alpha-1(IV) chain

Cat.:

U0180b

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Collagen alpha-1(IV) chain

Cat.:

U0180h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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CLIA Kit for Mouse Collagen alpha-1(IV) chain

Cat.:

U0180r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Collagen alpha-1(IV) chain

Cat.:

P0180Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Collagen alpha-1(IV) chain

Cat.:

P0180Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Collagen alpha-1(IV) chain

Cat.:

P0180Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Collagen alpha-1(IV) chain

Monoclonal Antibody for Mouse Collagen alpha-1(IV) chain

Protein for Mouse Collagen alpha-1(IV) chain

Cat.:

R0180h

Price:

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Packing:

1mg

Purity:

>90%

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"The complete primary structure for the alpha 1-chain of mouse collagen IV. Differential evolution of collagen IV domains."
Muthukumaran G. , Blumberg B. , Kurkinen M.
J. Biol. Chem.264:6310-6317(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
strain: C57BL/6J.
tissue: Brain.
tissue: Eye.
tissue: Heart.
tissue: Placenta.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
strain: FVB/N.
tissue: Brain.
tissue: Colon.
tissue: Mammary gland.
4.

"cDNA clones completing the nucleotide and derived amino acid sequence of the alpha 1 chain of basement membrane (type IV) collagen from mouse."
Wood L. , Theriault N. , Vogeli G.
FEBS Lett.227:5-8(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1154
5.

"Structure of the amino-terminal portion of the murine alpha 1(IV) collagen chain and the corresponding region of the gene."
Killen P.D. , Burbelo P.D. , Sakurai Y. , Yamada Y.
J. Biol. Chem.263:8706-8709(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-129
6.

"Characterization of the promoter for the alpha 1 (IV) collagen gene. DNA sequences within the first intron enhance transcription."
Killen P.D. , Burbelo P.D. , Martin G.R. , Yamada Y.
J. Biol. Chem.263:12310-12314(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28
7.

"Head-to-head arrangement of murine type IV collagen genes."
Kaytes P. , Wood L. , Theriault N. , Kurkinen M. , Vogeli G.
J. Biol. Chem.263:19274-19277(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28
8.

"Alpha 1(IV) and alpha 2(IV) collagen genes are regulated by a bidirectional promoter and a shared enhancer."
Burbelo P.D. , Martin G.R. , Yamada Y.
Proc. Natl. Acad. Sci. U.S.A.85:9679-9682(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28
9.

"Alpha 1 type IV collagen gene evolved differently from fibrillar collagen genes."
Sakurai Y. , Sullivan M. , Yamada Y.
J. Biol. Chem.261:6654-6657(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1110-1135
10.

"Isolation of an alpha 1 type-IV collagen cDNA clone using a synthetic oligodeoxynucleotide."
Nath P. , Laurent M. , Horn E. , Sobel M.E. , Zon G. , Vogeli G.
Gene43:301-304(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1149-1424
11.

"Amino acid sequence of the non-collagenous globular domain (NC1) of the alpha 1(IV) chain of basement membrane collagen as derived from complementary DNA."
Oberbaeumer I. , Laurent M. , Schwarz U. , Sakurai Y. , Yamada Y. , Vogeli G. , Voss T. , Siebold B. , Glanville R.W. , Kuhn K.
Eur. J. Biochem.147:217-224(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1276-1669
12.

"Extensive homology between the carboxyl-terminal peptides of mouse alpha 1(IV) and alpha 2(IV) collagen."
Kurkinen M. , Condon M.R. , Blumberg B. , Barlow D. , Quinones S. , Saus J. , Pihlajaniemi T.
J. Biol. Chem.262:8496-8499(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1441-1669
13.

"Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly."
Gould D.B. , Phalan F.C. , Breedveld G.J. , van Mil S.E. , Smith R.S. , Schimenti J.C. , Aguglia U. , van der Knaap M.S. , Heutink P. , John S.W.M.
Science308:1167-1171(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE

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